Manager - Molecular Diagnostics

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Overview

This position requires strong leadership qualities in building and working with the team of laboratory staff. Working independently, under general supervision of Medical Director, performs a variety of routine, but sophisticated Molecular protocols for diagnostic testing. Interprets quality controls on molecular biology assays. Through literature searches and conferences with Laboratory Director(s) and other Clinical Managers, may assist in determining the most suitable methodologies to be used.

This position is responsible for overseeing and managing the expansion of Molecular Diagnostics amongst various sites including the development of new sites. Provides excellent orientation and training of new and existing laboratory staff to include the development and implementation of proficiency and competency testing on a consistent basis. Applicant must have the ability to work collaboratively with contacts both internal and external to the laboratory, and to make decisions and direct the activities of others.

Responsibilities include:

• Oversees all operational aspects of multi-site labs.
• Manages and coordinates all laboratory staffing.
• Collaborate with section managers to improve end-to-end specimen flow, communication, and turnaround time.
• Work closely with peer leaders across Anatomic Pathology, including Histology, Immunohistochemistry (IHC), Cytology, and other laboratory sections, to support coordination of workflows and services.
• Contribute to initiatives aimed at streamlining processes and enhancing alignment across laboratory sections, while respecting established reporting structures.
• Partner with colleagues to identify opportunities for workflow integration and operational efficiencies.
• Support the department’s vision of a more unified and coordinated laboratory system, promoting consistency in processes and communication.
• Foster a collaborative environment built on shared goals, transparency, and mutual accountability.
• Optimize workflow, staffing, and performance metrics (TAT, productivity).
• Maintains diagnostic viability of specimens received. Prepares clinical specimens for testing, which includes handling of tissues and blood samples, centrifugation spectrophotometry, gel electrophoresis and robotic instrumentation.
• Utilizes protocols with a variety of molecular assays that are constantly evolving as the discipline develops, but includes PCR, RT-PCR, QRT-PCR, capillary gel electrophoresis, Sanger sequencing and next generation sequencing platforms.
• Accurately records all procedures and data in laboratory. Documents and follows up on any errors, failures, and quality assurance issues encountered.
• Responsible for organizing and executing entire day workload, which will vary and require adjusting to the clinical specimens obtained each day. Must work with other technologists and managers/supervisors as a team.
• Independently evaluates existing protocols and recommends changes.
• Actively participates in the validation of new clinical assays with attention to quality assurance and quality controls using good laboratory practice.
• Independently troubleshoots problems relating to routine operation of laboratory.
• Responsible for providing accurate patient information to clinicians as requested, following established laboratory protocols.
• Interprets quality controls on molecular assays. Responsible for documentation of daily QA/QC charts for all laboratory equipment and assays.
• Assists with the organization and tracking of data for the Proficiency testing program for the lab.
• Assists with cost analyses and budget development and monitoring.
• Orients and trains fellows, residents, students, new and less advanced technologists.
• Prepares or handles large inventory of varied reagents in the lab and maintains quality control of reagents.
• Assures that laboratory supplies are maintained and ordered as needed and assures sufficient inventory is available for anticipated test volumes.
• Actively works to identify the most appropriate suppliers.
• Assures that laboratory equipment is maintained in proper working order, following appropriate laboratory safety protocols.
• Ensure data integrity and regulatory compliance.
• Maintains established department policies, procedures and objectives, including the areas of quality assurance, safety, environmental and infection control.
• Play major role in assuring section compliance with all CMS, CLIA, CAP, Joint Commission, DPH, OSHA and other regulations including reporting of patient test results as required by regulatory agencies.
• Follows all JC National Patient Safety Goals and related Yale Pathology and Hospital Policies.
• Support and model organizational behavioral standards in maintaining a positive work.
• Required Skills and Abilities
• 1. Minimum 3 years of laboratory experience in Molecular biology.
• 2. Minimum 3 years management experience in a laboratory.
• 3. Proven experience with NGS and PCR.
• 4. Strong interpersonal, management and technical skills required.
• 5. High level verbal and written communication skills required. High level organizational and analytic skills required; ability to assess and redesign workflows as needed.
• Preferred Skills and Abilities
• 1. Bachelor’s Degree in Molecular Biology or related laboratory science required science.
• 2. MB (ASCP) Certification.
• 3. FISH experience.
• Principal Responsibilities
• 1. Reviews and determines staffing needs, job posting requirements, salary guidelines, and labor agreement interpretations for exempt and non-exempt staff in one or more functional department of the University. 2. Manages the administrative support needs for exempt and nonexempt staff and provides recommendations, improvements, solutions and assistance as needed. 3. Manages and monitors technology needs, conducts inventory, and system requirements for the assigned departments. 4. Develops and prepares budgets, financial forecasts, and financial analyses and the actual vs. budgeted performance reports for the departments. 5. Manages the use of facilities in one or more departments including office space, work stations, equipment, and office supplies. 6. Manages administrative support for activities of one or more departments to ensure timely completion of projects. 7. Manages and coordinates training sessions for assigned departments when new policies or practices are adopted. 8. Ensures compliance with University and federal regulations as they apply to the assigned departments. 9. Identifies, plans, and develops administrative policies for the assigned departments. 10. Assists in reviewing and implements University and departmental policies as they pertain to the administrative functions of the assigned department. 11. Assesses and makes recommendations regarding staff development and staffing levels. 12. Monitors, develops, plans, and executes systematic research on user requirements through such mechanisms as surveys, interviews, focus groups and competitive analysis. 13. Manages a staff of exempt and non-exempt employees. 14. May perform other duties as assigned.
• Required Education and Experience
• Bachelor’s Degree in related field and 5 years of experience or an equivalent combination of education and related experience.
• Job Posting Date
• 10/13/2026
• Job Category
• Manager
• Bargaining Unit
• NON