Scientist 2, Translational CVRM

The Opportunity

The CVRM (Cardiovascular, Renal, and Metabolism) Translational Biology group within Genentech Research and Early Development (gRED) is seeking a highly motivated and well-trained individual to advance drug discovery research and development efforts by executing in vivo experiments in rodent models of cardiometabolic diseases. This position requires working closely with scientists in a multidisciplinary team.

Our environment is exciting and fast paced, requiring you to be excellent at multitasking and easily adaptable to meet evolving goals. This is an exciting opportunity to join a growing CVRM biology group and make significant contributions.

Key Responsibilities:

• Establish and conduct experiments in relevant rodent models and optimize approaches to model disease processes and states which resemble human diseases
• Generate high-quality experimental data to meet strict timelines and project goals.
• Communicate key findings at project meetings and make recommendations for follow-up studies and prioritization.
• Familiar with relevant scientific literature. Understand and apply relevant scientific knowledge to solving problems arising from the projects involved
• Work collaboratively within multidisciplinary project teams
• Generate, analyze, and document complex experimental data with a focus on high reproducibility, maintaining accurate Electronic Lab Notebook (ELN) records.
• Who You Are
• Bachelor’s degree in pharmacology, biology, or related fields with 6+ years of laboratory experience, OR a Master’s degree with 4+ years of experience in industry or academia
• A detail-oriented researcher who is passionate about leveraging best disease modeling to accelerate our research and discovery
• Hands-on experience with cardiovascular models (myocardial infarction/ischemia–reperfusion, transverse aortic constriction) and their phenotyping (echocardiography, heart catheterization). Proficient survival surgical skills in rodents
• Experience with rodent handling, various routes of drug administration (intravenous, intraperitoneal, intramuscular and subcutaneous), non-terminal and terminal blood sampling and tissue harvest.
• Strong analytical, organizational and communication skills
• Highly motivated, self-driven person, comfortable working independently or as team in a fast-paced environment
• Willingness to learn new skills and rapidly adapt to changing priorities for multiple projects.
• Preferred
• Experience with other cardiometabolic disease models will be a plus.
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• Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $85,500 to $158,700.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.