Research Postdoctoral Fellow - Long Laboratory

SHIFT:

Day (United States of America)

Seeking Breakthrough Makers

Children’s Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation.

At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care—and your career.

CHOP does not discriminate on the basis of race, color, sex, national origin, religion, or any other legally protected categories in any employment, training, or vendor decisions or programs. CHOP recognizes the critical importance of a workforce rich in varied backgrounds and experiences and engages in ongoing efforts to achieve that through equally varied and non-discriminatory means.

A Brief Overview

Under the direction/guidance of a mentor (principal investigator), assumes responsibility for a specific, on-going research project. The experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities. It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group.

This role will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results. This position will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings. This role also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.

Under the direction/guidance of a mentor (principal investigator), assumes responsibility for specific, on-going or new research projects. The experience will serve to extend, refine and enhance skills necessary for professional and career development, and will enable the individual to broaden his/her scientific background by acquiring new research capabilities.

It is expected that this individual will conduct independent scholarly research, and will contribute directly to the overall research goals of the project and the research group.

This role will be expected to participate in project planning, recording and interpretation/evaluation of data, and communication of results. This position will also be expected to acquire technical, lab management, and manuscript/grant writing skills; and participate in seminars, lectures, poster sessions and presentations at national meetings. This role also may be required to supervise junior lab members, develop new methods and protocols for research, and assist with the development of other research projects in the lab.

About the Laboratory

The Long Laboratory investigates the cellular and molecular mechanisms underlying skeletal development, bone homeostasis, and disease, with a particular focus on skeletal stem and progenitor cells, cellular metabolism, and the integration of bone and whole-body metabolism. Research combines genetic mouse models, developmental biology and biochemical approaches to define disease mechanisms and identify potential therapeutic targets.

Ongoing Projects:

Bone Metabolism in Diabetes: Investigating the cellular and molecular basis of bone fragility and increased fracture risk in diabetes animal models, with the goal of identifying new therapeutic targets.

Skeletal Metabolism: In vitro biochemical and in vivo genetic studies of major metabolic pathways in skeletal cell types during normal development, homeostasis and bone repair .

Skeletal Stem and Progenitor Cells: Investigating the identity, location, and regulation of skeletal stem and progenitor cells that build, maintain and repair the mammalian skeleton. Age-dependent changes in the stem and progenitor cells are evaluated as a basis for bone aging.  Ongoing studies use single cell technology and genetic lineage-tracing methods in animal models to identify and track these cells.

Lab link : https://www.research.chop.edu/long-laboratory

What you will do

• Conduct independent scholarly research and develop new methods and protocols
• Participate in project planning, recording and evaluation of data
• Acquire technical, lab management and grant writing skills
• Participate in seminars, lectures, poster sessions and presentation at national meetings
• Supervise junior lab members
• Assist with other research projects
• Education Qualifications
• Doctorate Required
• Skills and Abilities
• Ability to wear a respirator device
• To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine. Learn more.
• EEO / VEVRAA Federal Contractor | Tobacco Statement