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Job opportunity
Principal Analyst, Clinical Data Ingestion
New York
Source: H1 careers · View original posting
- Pay
- $170,000 — $200,000 USD per year
Employer job description
From H1's posting. “We” and “our” refer to the employer.
At H1, we believe access to the best healthcare information is a basic human right. Our mission is to provide a platform that can optimally inform every doctor interaction globally. This promotes health equity and builds needed trust in healthcare systems.
To accomplish this our teams harness the power of data and AI-technology to unlock groundbreaking medical insights and convert those insights into action that result in optimal patient outcomes and accelerates an equitable and inclusive drug development lifecycle. Visit h1.co to learn more about us.
We are seeking a senior clinical data expert to lead the strategy for the clinical data that powers our platform. You will be the authority on which clinical data sets we acquire, how they are structured and interpreted, and how they are made trustworthy: standards of care, drug lists, study start-up and regulatory cycle times, CTMS data, and other clinical and trial operations sources.
WHAT YOU'LL DO AT H1
- Define the clinical data acquisition strategy: which sources to bring in, in what priority, and whether to build, buy, or partner
- Serve as the subject matter expert on clinical data content, including standards of care, drug lists, study start-up times, regulatory cycle times, and CTMS data
- Specify how each data set should be modeled, normalized, and mapped to standard vocabularies, and document the business rules and definitions behind them
- Set data quality standards and acceptance criteria (completeness, accuracy, freshness, consistency), and review source data and ingested output against them
- Partner with data engineering on ingestion requirements, source onboarding, and prioritization; hold engineering accountable to data quality outcomes, but do not own pipeline build or operations
- Evaluate and onboard data partners and vendors, assessing coverage, provenance, and fitness for use
- Partner with H1 product teams to decide which data sources to prioritize and how each one serves H1 products and customer use cases; translate product needs into data acquisition priorities, and work with data science and commercial teams to make sure ingested data supports them
- Work with legal, privacy, and compliance on data-use terms and de-identification requirements
- Influence the data roadmap and represent clinical data expertise to executive leadership, customers, and external partners.
ABOUT YOU
You are a senior individual-contributor and thought-leader, and you enjoy working cross-functionally, leading with influence by building trust and confidence in your judgment and expertise. You will partner closely with the engineers who build and run the ingestion pipelines, setting the requirements, definitions, and quality bar, while the pipeline build itself sits with the engineering team.
REQUIREMENTS
- 7+ years of experience in clinical, healthcare, or life sciences data, with deep hands-on expertise in clinical trial operations data and real-world clinical data
- Demonstrated expertise in at least two of the following data domains (all preferred), including how each is sourced, structured, and used:
- Standards of care
- : clinical guidelines and treatment pathways (e.g., NCCN, ASCO, specialty society guidelines) and how they map to real-world practice
- Drug lists
- : formularies, drug compendia, and reference lists (e.g., NDC, RxNorm, ATC), including brand/generic and indication mapping
- Study start-up times
- : site identification, contracting, IRB/ethics approval, and activation timelines across sites and countries
- Regulatory cycle times
- : submission-to-approval timelines across agencies and regions (e.g., FDA, EMA, PMDA, NMPA)
- CTMS data
- : sites, enrollment, milestones, monitoring, and operational performance
- Working knowledge of clinical and coding standards (e.g., OMOP, FHIR, HL7, ICD-10, CPT, NDC, LOINC, SNOMED) and data quality frameworks
- Track record of defining data requirements and quality standards that engineering teams build against
- Experience evaluating and working with external data vendors and partners
- Ability to partner with product teams to link data sources to product value and prioritize them accordingly
- Ability to explain complex clinical data topics clearly to executives, engineers, and customers
- Hands-on comfort with SQL or equivalent to profile, validate, and investigate data issues
- Preferred
- Bachelor’s degree in a scientific or technical field; advanced degree (e.g., PharmD, MPH, PhD) a plus
- Background at a pharma, CRO, healthcare data, or health-tech company
- Experience with CTMS, EDC, or clinical operations platforms
- Familiarity with entity resolution, master data management, or AI/ML-assisted data mapping and validation
- Experience mentoring or informally leading cross-functional teams without direct reports
Compensation
COMPENSATION
This role pays $170,000 to $200,000 per year, based on experience, in addition to equity in the form of Restricted Stock Units.
Anticipated role close date: 12/21/2026
H1 OFFERS
- Full suite of health insurance options, in addition to generous paid time off
- Pre-planned company-wide wellness holidays
- Retirement options
- Health & charitable donation stipends
- Impactful Business Resource Groups
- The opportunity to work with leading biotech and life sciences companies in an innovative industry with a mission to improve healthcare around the globe
H1 is committed to working with and providing access and reasonable accommodation to applicants with mental and/or physical disabilities. If you require an accommodation, please reach out to your recruiter once you've begun the interview process. All requests for accommodations are treated discreetly and confidentially, as practical and permitted by law.
Employer application notice
Equal opportunity and accommodations
H1 is proud to be an equal opportunity employer that celebrates diversity and is committed to creating an inclusive workplace with equal opportunity for all applicants and teammates. Our goal is to recruit the most talented people from a diverse candidate pool regardless of race, color, ancestry, national origin, religion, disability, sex (including pregnancy), age, gender, gender identity, sexual orientation, marital status, veteran status, or any other characteristic protected by law.
About this listing
LAYIQ is an independent job-discovery service. This listing does not imply a partnership with or endorsement by the employer. Review the original posting for current details and availability.
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