Registered Nurse II/III Human Genetic Outpatient

• Primary Location
• Location E Department
• Amb Svcs Human Genetics Shift
• Day (United States of America) Schedule
• Full time Weekly Hours

32 FTE

0.8 Employee Status

Regular

• Registered Nurse II or III – Human Genetics
• Full-Time 32 hours / week
• Make a Difference in the Lives of Children with Rare Genetic Conditions

Cincinnati Children’s is seeking an experienced Registered Nurse II or III to join our Human Genetics team, supporting our Lysosomal Storage Disease Program. This is an exciting opportunity for a nurse who is passionate about caring for children and adults and families with complex, rare genetic and metabolic conditions.

Working alongside a collaborative team of Genetic Counselors (GCs), Advanced Practice Registered Nurses (APRNs), physicians, and other healthcare professionals, this nurse will play an important role in coordinating comprehensive patient care, supporting disease-specific treatment plans, and serving as a trusted resource for patients and families.

This position offers a combination of clinical responsibilities in the outpatient setting and office-based care coordination. The ideal candidate is an organized, proactive nurse who enjoys building relationships, advocating for patients, navigating complex healthcare needs, and collaborating with a multidisciplinary team.

Key Responsibilities

• Clinical Care & Patient Coordination
• Serve as a primary clinical point of contact for patients and families diagnosed with lysosomal storage disorders, including Gaucher disease, Fabry disease, Pompe disease, MPS disorders, and other rare metabolic conditions.
• Provide nursing support during outpatient clinic visits and coordinate ongoing patient care in collaboration with Genetic Counselors, APRNs, physicians, and multidisciplinary teams.
• Coordinate comprehensive, longitudinal care plans across multiple specialties, including genetics, neurology, cardiology, pulmonology, nephrology, orthopedics, rehabilitation services, and primary care.
• Facilitate referrals, consultations, diagnostic testing, and follow-up appointments to promote continuity of care.
• Monitor disease progression, treatment response, and emerging clinical concerns, communicating changes to the medical team.
• Assist providers in developing individualized treatment plans based on disease-specific needs and patient goals.
• Treatment & Therapy Coordination
• Coordinate the initiation and ongoing management of enzyme replacement therapies (ERT), substrate reduction therapies, and other disease-specific treatments.
• Collaborate with home infusion agencies, specialty pharmacies, infusion centers, insurance providers, and pharmaceutical support programs to facilitate timely and uninterrupted treatment.
• Monitor treatment adherence and identify barriers to medication access or administration.
• Assess and coordinate follow-up for infusion-related concerns, adverse events, trouble shooting with access ports and treatment complications in collaboration with the medical team.
• Track treatment schedules and ensure appropriate laboratory monitoring is completed according to established protocols.
• Patient & Family Advocacy
• Serve as a resource and advocate for patients and families navigating complex healthcare needs.
• Assist families in accessing community, educational, financial, and psychosocial resources.
• Advocate for patient needs related to school accommodations, therapy services, durable medical equipment, and community support.
• Facilitate transitions of care between pediatric and adult healthcare systems.
• Support patients and families during hospitalizations, emergency department visits, and significant changes in clinical status.
• Build meaningful relationships with patients and families while providing education, guidance, and ongoing support throughout their healthcare journey.

Qualifications

• Bachelor’s degree in nursing (BSN).
• 5 years nursing experience
• Current Ohio RN license.

Preferred Qualifications:

• Pediatric nursing experience.
• Experience in genetics, metabolic disorders, specialty clinics, or complex care coordination.
• Knowledge of rare genetic conditions, enzyme replacement therapies, or specialty medication management.
• Experience coordinating care across multiple specialties and collaborating with multidisciplinary teams.
• Strong communication, organizational, critical-thinking, and patient advocacy skills.
• Why Cincinnati Children's?
• At Cincinnati Children's, our teams are dedicated to improving the health of children through exceptional clinical care, research, and innovation. Join a collaborative Human Genetics team where your nursing expertise will make a meaningful difference in the lives of children and families affected by rare and complex conditions.
• If you are a compassionate, organized nurse who enjoys complex care coordination, patient advocacy, and working with a dedicated multidisciplinary team, we invite you to explore this opportunity!
• JOB RESPONSIBILITIES
• Compliance - Patient Services Staff - Sustain a working understanding of regulatory requirements and accreditation standards. Support leadership in Compliance efforts to meet and sustain the regulatory compliance efforts of the department and hospital. Be mindful and judicious in monitoring safety and departmental policies and procedures. Ensure all individual certifications and Safety College requirements are fulfilled in a timely basis. Work with department managers, nurse council and magnet representatives to identify and share safety best practices. Be mindful of CCHMCs processes and compliance with CMS standards and freely communicate safety and compliance concerns to leadership team members.
• Interprofessional Practice -  Demonstrates consistent integration of the Interprofessional Practice Model (IPM) in all aspects of practice.
• Clinical inquiry & performance review to improve practice -  Follows standards and guidelines; implements clinical changes and research-based practices developed by others; recognizes the need for further learning to improve patient care; recognizes routine or obvious changing patient situation (e.g., deterioration, crisis); in unusual care situations, seeks help when needed to identify patient problem. Uses self-appraisal performance review and peer review, including annual goal setting, for assurance of competence and professional development to promote safe and ethical practice using the nursing process. Demonstrates openness to coaching and mentoring from others. Facilitates learning by assisting with peer and student learning experiences. Works with department managers, nurse council and magnet representatives to identify, share, implement and evaluate safety best practices.
• Uses systems thinking -  Sees the pieces or components; sees patient and family within the isolated environment of the unit; sees self as key resource to support the family through the healthcare experience through care coordination. Sustains a working understanding of regulatory requirements and accreditation standards. Supports leadership in efforts to meet and sustain the regulatory compliance efforts of the department and hospital. Monitors and complies with safety and departmental policies and procedures. Ensures individual certifications and Safety College requirements are fulfilled in a timely basis. Is mindful of CCHMCs processes and compliance with CMS standards and freely communicates safety and compliance concerns to leadership team members.
• Patient Care - Age Specific and Culturally Inclusive - Consistently integrates age specific and culturally inclusive concepts into patient care, taking into consideration both the patient's chronological age and developmental functioning.
• Collaborates with team using shared decision making -  Is receptive to the contributions of the interdisciplinary team in team meetings and discussion regarding patient issues. Participates in shared governance at the point-of-care as a member of unit-based councils or by demonstrating awareness and contributing to shared decision making (reading minutes, giving feedback and implementing council decisions).
• Clinical judgment when performing caring practices -  Collects clinical data; follow algorithms, decision trees, and protocols. Matches formal knowledge with clinical events to make appropriate decisions; uses available resources as needed. Documents plan of care, care delivered, and patient and family outcomes. Focuses on the usual and customary needs of the patient and family; anticipates future needs; bases care on standards and protocols; maintains a safe physical environment; acknowledges death as a potential outcome. Consistently integrates age specific concepts into patient care, taking into consideration both the patient's chronological age and developmental functioning. Using self-management support, develops care goals and actions through partnerships with patients and families. Facilitates patient and family learning by providing structured education based on the plan of care goals, and the needs of the patient and family; uses teach back to evaluate effectiveness.
• Exhibits advocacy, moral agency and response to inclusion - Works on behalf of patient and family; assesses personal values; aware of ethical conflicts/issues that may surface in clinical setting; makes ethical/moral decisions based on rules; represents patient when patient cannot represent self; aware of patients' rights. Assesses cultural inclusion. Recognizes the potential impact of culture on the patient/family experience and incorporates culturally inclusive concepts into patient care.

About Us

At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.

Cincinnati Children's is:

• Recognized by U.S. News & World Report as a  top 10   best Children's Hospitals in the nation for more than 15 years
• Consistently among the top 3 Children's Hospitals for National Institutes of Health (NIH)  Funding
• Recognized as one of America’s Best Large Employers   (2025) , America’s Best Employers for New Grads (2025)
• One of the nation's  America’s Most Innovative Companies  as noted by Fortune
• Consistently certified as great place to work
• A Leading Disability Employer  as noted by the  National Organization on Disability
• Magnet® designated for the fourth consecutive time by the  American Nurses Credentialing Center (ANCC)

We Embrace Innovation—Together.  We believe in empowering our teams with the tools that help us work smarter and care better. That’s why we support the responsible use of artificial intelligence. By encouraging innovation, we’re creating space for new ideas, better outcomes, and a stronger future—for all of us.

Comprehensive job description provided upon request.