Research Opportunities - Gastroenterology (Hepatology)

Location

SAINT LOUIS, MO 63110

 Scheduled Hours

40

Position Summary

The Schwartz Laboratory in the Division of Gastroenterology, Department of Medicine, at Washington University School of Medicine in St. Louis is seeking motivated and creative technicians, scientists and postdocs to join our interdisciplinary research program investigating: the biology of hepatitis B virus (HBV) and the mechanisms that allow the virus to establish and maintain chronic infection; how SARS-CoV-2 and other respiratory pathogens interact with human tissue; working at the forefront of human liver tissue engineering and

regenerative medicine; the fundamental cell biology of the liver; how hepatocytes, cholangiocytes, stromal and endothelial cells establish and maintain liver architecture, respond to injury, and regenerate; and how metabolic dysfunction, cellular communication, and genetic alterations contributing to liver disease and cancer.

Our long-term goals are: to understand the complex interactions between HBV and its host that drive viral persistence and to use these insights to identify new strategies toward a functional cure for chronic hepatitis B, which remains a major global health challenge and an important cause of liver-related morbidity and mortality; to establish a multi-organ organoid and stem cell-derived platform that contributes to our understanding of viral pathogenesis and host immune responses; to develop GMP-grade, hypoimmunogenic bioartificial

liver for transplantation; to determine how the different liver cells respond to injury and their impacts on regeneration and fibrosis; and to uncover fundamental mechanisms of disease and identifying new opportunities for therapeutic intervention.

We are seeking individuals with prior experience in molecular biology, biochemistry, genetics and/or cell biology.

Projects and requirements will vary depending on candidate background and experience.

Job Description

Primary Duties & Responsibilities:

Working Conditions:

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Education:

Bachelor’s degree or combination of education and/or experience may substitute for minimum education.

Certifications /Professional Licenses :

No specific certification/professional license is required for this position.

Work Experience:

No specific work experience is required for this position.

Skills:

Not Applicable

Driver's License:

A driver's license is not required for this position.

More About This Job

Preferred Qualifications:

• Experience with mouse handling, husbandry, and/or survival surgery.
• Experience in liver, gastrointestinal, or developmental biology research.
• Experience with primary hepatocyte or other primary cell culture.
• Experience in histology, immunofluorescence, or imaging-based analysis.
• Experience in bioengineering.
• Experience in molecular virology.
• Demonstrated analytical, reasoning and problem-solving skills.
• Ability to analyze and interpret statistical data and to communicate data in a clear, concise manner.
• Adept at using Microsoft Office Suite and the ability to use software packages to analyze data.

Preferred Qualifications

• Education: No additional education unless stated elsewhere in the job posting.
• Certifications/Professional Licenses : No additional certification/professional licenses unless stated elsewhere in the job posting.
• Work Experience: No additional work experience unless stated elsewhere in the job posting.
• Skills: Communication, Laboratory Research, Organizing, Recordkeeping, Working Independently
• Grade
• 00
• Questions
• For frequently asked questions about the application process, please refer to our External Applicant FAQ .
• Accommodation
• If you are unable to use our online application system and would like an accommodation, please email  CandidateQuestions@wustl.edu  or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
• All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.
• Pre-Employment Screening
• All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.