Senior Director, Clinical Pharmacology

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits.

This is work that transforms the lives of patients, and the careers of those who do it.

Position Summary

The Senior Director, Clinical Pharmacology provides strategic and scientific leadership for clinical pharmacology activities across drug development programs. This role leads the planning and execution of clinical pharmacology strategies, including PK/PD and model-informed drug development approaches, and oversees development and delivery of Clinical Pharmacology & Pharmacometrics plans aligned with compound strategy.

The Senior Director serves as a key member of Clinical Pharmacology leadership and cross-functional program teams, influencing development strategy and decision-making while fostering a collaborative, high-performing learning environment.

Key Responsibilities

• Manage and mentor other CP&P leads as appropriate
• Responsible and accountable for clinical pharmacology strategy across all phases of development
• Represent the ClinPharm department on cross-functional disease strategy teams and on relevant governance forums
• Provide input to Phase 2/3 clinical study design and registrational strategy
• Supervise the development of the Clinical Pharmacology Plan(s)
• Supervise design of Clinical Pharmacology studies and manages data analysis, interpretation, and reporting
• Drive decision-making and strategy over the entire portfolio or critical portions of the portfolio of compounds, through effective partnership with senior leaders
• High proficiency in PK, PK/PD, and model informed drug development (MIDD) principles and analyses
• Lead collaboration on cross-functional drug development teams, regulatory submissions, and departmental initiatives; serves as Clinical Pharmacology subject matter expert
• Represent department in interactions with health authorities; serve as Clinical Pharmacology subject matter expert
• Oversee internal initiatives and serves as department representative on external initiatives
• Work with Business Development teams and provide critical expertise to assess external acquisitions
• Responsible for administrative deliverables such as creating Therapeutic area level departmental objectives, hiring / retaining talent, maintaining budgets, etc.
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Qualifications & Experience

• MS, PhD or PharmD in relevant field or a PharmD with post-doctoral training
• Approximately 10+ years’ experience with demonstrated progression in Clinical Pharmacology and Pharmacometrics, including extensive expertise in the general drug development process and in small molecule and/or biologic drug property characterization
• In-depth knowledge of current practices and issues in Clinical Pharmacology and Pharmacometrics
• Strong written and oral communication skills necessary to report on and deliver scientific presentations
• Demonstrated ability to work in a dynamic team-oriented environment
• Manage a team of CP&P scientists and provide mentorship and guidance to staff and CP&P function
• Independently serve as the CP&P lead for one or more assets in the BMS drug development program
• Demonstrated leadership abilities, expanded sphere of influence, and stakeholder management in a matrix environment
• Programming experience is highly desired (e.g., NONMEM, R, and WinNonlin. SAS, Splus, etc.)
• Quantitative data analysis, POP PK/PD, and data visualization skills are highly desired
• We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.